Access OpenAI GPT models on Amazon Bedrock from Canada with cross-Region inference

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What happened
Canadian organizations can now access OpenAI GPT-5.6, GPT-6, and GPT-6.1 models on Amazon Bedrock from the Canada (Central) and Canada West (Calgary) Regions using cross-Region inference. This post covers the models and inference profiles, how to set up permissions, and how to invoke them with the Responses, Chat Completions, and Converse APIs.
Summary assembled by rule from the sources below