College football picks: USC set to knock off Ducks as teams enter meat of season in prove-it mode

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Also, can No. 4 Mississippi validate its win over LSU with another one as an underdog at No. 21 Florida or are the Gators really good; is No. 17 Iowa's offensive improvement fool's gold or will it get shut down at No. 18 Michigan; and will No. 13 Penn State keep rolling in its Big Ten opener against Wisconsin after playing a light nonconference schedule? That's just a sample of the questions to be answered as the se…

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